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conferenceseries
.com
6
th
World Congress on
October 16-18, 2017 | San Francisco, USA
Breast Cancer & Therapy
Volume 2, Issue 5 (Suppl)
Breast Can Curr Res, an open access journal
Breast Cancer Congress 2017
October 16-18, 2017
Pregnancy associate breast cancer: A single institute experience from developing country
Pooja Gogia
Artemis Hospital, India
P
regnancy-associated breast cancer (PABC) has been defined as breast cancer diagnosed during pregnancy or within 1 year of
delivery. There is a paucity of data on PABC from India. The aim of our study was to assess the clinical-pathological parameters
and outcome of PABC at our centre. We screened approximately 3,750 cases registered in between a period of 11 years. The median
age was 26 years (range 20-35). The median duration of symptoms was 11.5 months. The American Joint Committee on Cancer stage
distribution was Stage I - 1, Stage II - 3, Stage III - 14 and in Stage IV - 8 patients. Median clinical tumor size is 5.5 cm. Four patients
were presented with the inflammatory breast cancer. Positive family history was elicited in three patients. Twenty-one patients were
diagnosed after delivery, two patients in the first trimester, two patients in the second trimester and three patients in the third
trimester. Estrogen receptor (ER), progesterone receptor (PR) negativity and human epidermal growth factor receptor 2 (HER2/neu)
positivity was 56% and 38%, respectively. Nearly, 40% of patients had a high-grade tumor and 70% had pathological node positivity.
With a median follow-up of 33 months, 3 years relapse free survival and overall survival was 40% and 50% respectively. Bone was the
most common site for systemic relapse. PABC constituted 0.7% of all breast cancer patients. It is associated with advanced stage at
presentation. Half of them were ER/PR negative and one-third was HER2/neu positive.
poojakhullarg@gmail.comBreast Can Curr Res 2017, 2:5 (Suppl)
DOI: 10.4172/2572-4118-C1-012