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Biopolymers and Bioplastics 2016
September 12-14, 2016
Volume 7, Issue 5(Suppl) J Bioremed Biodeg 2016
ISSN: 2155-6199 JBRBD, an open access journal
conferenceseries .com
September 12-14, 2016 San Antonio, USA
3rd International Conference and Exhibition onBiopolymers & Bioplastics
Rebeca Betancourt Galindo et al., J Bioremed Biodeg 2016, 7:5(Suppl)
Zinc oxide nanoparticles control skin infection and improve dermal wound healing in humans
Rebeca Betancourt Galindo1, Juan Bernal Martínez2, Antonio Camacho Manriquez 3, Carlos Ávila Orta1 and B Puente Urbina1
1Centro de Investigación en Química Aplicada, México
2Unidad Medica Ojo Caliente, México
3Hospital General de Saltillo, México
Zinc Oxide nanoparticles (ZnO-Naps) have been used in different bionanocomposites for wound healing and skin infection
based in the antibacterial intrinsic properties. However controversial toxic effects have been identified and preliminary
results observed in animal models give limitations for the uses of this nanoparticles in humans. Here we report the benefits
observed in dermal wound healing and control of infection in patient diagnosed with allergic dermatitis associated with infected
ulcers. Nanotechnology is considered as a multidisciplinary area that is part of nano scale systems that is very important from
the materials science, colloidal science, and medical science, among others. Currently nanotechnology is a rapidly growing area
primarily for biotechnology and medicine in both the development of new diagnostic techniques and therapeutic treatments
aimed at organs and damaged tissues. One of the alternatives with the greatest potential application is the use of ZnO-Naps
as an antimicrobial agent and ulcer healing properties. The mechanisms of action are: 1) Cofactor in enzymatic complexes
that promote migration of keratinocytes 2) participates in the formation of reactive oxygen species (ROS) which penetrate the
bacterial cell membrane producing oxidant injury. According to the mechanisms of action of ZnO Naps could be an alternative
as promoters of healing in chronic diabetic foot ulcers and other ulcers associated with allergic dermatitis. The objective of this
work is to assess the effectiveness of dressings of calcium alginate impregnated with ZnO-Naps, along with the local application
of powder of ZnO-Naps, in the control of infection and healing of ulcers in patients with allergic dermatitis.
Biography
Rebeca Betancourt Galindo is a Researcher at the Department of Advanced Materials. She has extensive experience in emulsion polymerization, polymer
and nanoparticle functionalization, preparation and physico-chemical characterization of polymer nanocomposites, including the determination of antimicrobial
properties of polymer nanocomposites. She has published more than 29 papers in reputed journals.