biomaterials-2018-scientifictracks-abstracts

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Volume 8

Journal of Biotechnology and Biomaterials

ISSN: 2155-952X

Biomaterials 2018

March 05-06, 2018

March 05-06, 2018 | Berlin, Germany

Annual Conference and Expo on

Biomaterials

Polymeric materials for ophthalmological applications

M Helena Gil, A Jorge Guiomar, Patrícia Alves

and

Filipa A M M Gonçalves

University of Coimbra, Portugal

owadays, both synthetic and natural polymeric materials have been applied in the ophthalmologic area. In our group some

work has been done on the development of intraocular lenses (IOLs) as well as on soft contact lenses (SCLs) for endophthalmitis

prophylaxis in cataract surgery and implantable disks for glaucoma treatment. The use of ocular controlled drug delivery systems

after ocular surgery is being used as an alternative to the usual eye drop administration. The development of SCLs based on acrylic

monomers for this purpose is the subject of our more recent study. Some membranes were prepared by bulk polymerization using

different monomers, such as ethylhexyl methacrylate, methyl methacrylic acid and a crosslinking agent, and were characterized

physical and chemically. To increase their performance as drug delivery systems, the surface membranes were also modified by

using either graft copolymerization or plasma treatment. All the copolymers were loaded with several ophthalmologic drugs and

used for drug release studies.

Recent publications

1. Vieira A P, Pimenta A F, Silva D, Gil M H, Alves P, Coimbra P, Mata J L, Bozukova D, Correia T R, Correia I J, Serro

A P and Guiomar A J (2017) Surface modification of an intraocular lens material by plasma-assisted grafting with

2-hydroxyethyl methacrylate (HEMA), for controlled release of moxifloxacin. European Journal of Pharmaceutics and

Biopharmaceutics 120:52-62.

2. Moura M J, Brochado, J Gil, MH and Figueiredo MM (2017)

In situ

forming chitosan hydrogels: Preliminary evaluation

of the

in vivo

inflammatory response. Materials Science & Engineering C-Materials for Biological Applications 75: 279-

285.

3. Carreira A S, Teixeira R F A, Beirdo A, Vieira R V, Figueiredo M M and Gil M H (2017) Preparation of acrylic based

microcapsules using different reaction conditions for thermo-regulating textiles production. European Polymer Journal

93:33-43.

4. Ferreira P, Alves P, Coimbra P and Gil MH (2015) Improving polymeric surfaces for biomedical applications: a review.

Journal of Coatings Technology and Research 12:463-475.

5. Carreira A S, Ferreira P, Ribeiro M P, Correia T R, Coutinho P, Correia I J and Gil M H (2014) New drug-eluting lenses

to be applied as bandages after keratoprosthesis implantation. International Journal of Pharmaceutics 477:218-226.

M Helena Gil et al., J Biotechnol Biomater 2018, Volume 8

DOI: 10.4172/2155-952X-C1-088