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Volume 8
Journal of Biotechnology and Biomaterials
ISSN: 2155-952X
Biomaterials 2018
March 05-06, 2018
March 05-06, 2018 | Berlin, Germany
3
rd
Annual Conference and Expo on
Biomaterials
J Biotechnol Biomater 2018, Volume 8
DOI: 10.4172/2155-952X-C1-089
Properties of bio-compatible polymers for 3d nanostructuring
Boris Buchroithner
Johannes Kepler University, Austria
T
wo-Photon Polymerization (2PP) allows fabrication of arbitrary three-dimensional structures in the sub-micrometer
range with controllable spatial and material properties. For 2PP a liquid resin consisting of cross-linkable monomers and
a small amount of a photo initiator is used as matrix for writing. Femtosecond laser pulses and a high numerical aperture
objective are used to create a focal volume with a high energy density. Therefor a simultaneous absorption of two photons
by the photo initiator is probable. The excited photo initiator decays than into a chemical active radical, which starts the
radical polymerization. Thus the cross-linking of the monomers yields the solidification of the polymer. Recent advances in
three-dimensional nanolithography for tissue engineering requires for non-toxic materials mimicking tissue properties (eg.
the extracellular matrix or cartilage). Typically for 3D lithography acrylate monomers are used because of their high reactivity.
However, they are toxic. Up to now mostly methacrylates are used. However they are less reactive and therefore require a
lower manufacturing velocity. In this work we present a new type of biocompatible polymer, which combines the reactivity of
acrylates, the biocompatibility of methacrylates and the stability of thiols. The resins are structured using 2PP with a 515nm
light source, a writing speeds up to several mm/s and sub-micrometer feature sizes. In order to characterize the mechanical
properties of the manufactured scaffolds, atomic force microscopy (AFM) was used. The polymers Young's modulus have been
characterized and compared to different available resins.
boris.buchroithner@jku.atm