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December 03-04, 2018 | Chicago, USA
American Pathology and Oncology Research
&
15
th
International Congress on
Microbial Genetics and Molecular Microbiology
International Conference on
Journal of Clinical & Experimental Pathology | ISSN: 2161-0681 | Volume 8
Probiotics with
Lactobacilli
origin differently act on the growth of hospital-acquired multidrug-
resistant
Klebsiella Pneumoniae
Lilit Malkhasyan
1
and
Astghik Z Pepoyan
2
1
International Association for Human and Animals Health Improvement, Armenia
2
Armenian National Agrarian University, Armenia
T
he positive effects of probiotic
lactobacilli
on human organism are known. Previously we suggested the use of Verhulst's
equation (VE) for the evaluation of the growth of gut isolates from the patients with Familial Mediterranean fever disease.
We used VE for the characterization of the growth of hospital-acquired multidrug-resistant
Klebsiella pneumoniae
strain in
current investigations. The differences in the duration of the growth preparatory and logarithmic phase, as well as in the
specific growth rate of the pathogen were detected under the influence of putative probiotic
lactobacilli
strains:
L. rhamnosus
str. Vahe,
L. rhamnosus
str. ASAP,
L. rhamnosus
str.
Lacto-G
,
L. plantarum
str. ZPZ and
L. delbrueckii
str. IAHAHI. The strain-
specific effects of
lactobacilli
on pathogen's growth show a possibility to use VE in the design of pharmacokinetics of probiotics.
This study was supported by the International scientific Technical Center (A-2134).
Biography
Lilit Malkhasyan received her MSc from the Armenian National Agrarian University (specialty:children and functional nourishment technology). She is an active
member of the International Association for Human and Animals Health Improvement, Yerevan, Armenia. She is the author of three scientific publications.
lmalkhasyan@gmail.comLilit Malkhasyan et al., J Clin Exp Pathol 2018, Volume 8
DOI: 10.4172/2161-0681-C5-058