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conferenceseries
.com
Volume 6, Issue 4 (Suppl)
Agrotechnology, an open access journal
ISSN: 2168-9881
Agri 2017
October 02-04, 2017
allied
academies
10
th
International Conference on
AGRICULTURE & HORTICULTURE
October 02-04, 2017 London, UK
Anti-adipogenic effect of
Moringaoleifera
leaves extract inporcinebonemarrowderivedmesenchymal
stem cells
Kulisara Marupanthorn
Rajamangala University of Technology, Thailand
M
oringa Oleifera
leaves (MOL) extract was used as a traditional medicine. Recent year, many published studies have shown
that alcohol, hydroalcohol, or water extracts of MOL possess a wide range of additional biological activities including
antioxidant, anti-diabetic, and anti-obesity. Among these characteristics representing some of the hallmarks of metabolic
syndrome, adipocytes also play an important role in this process through their metabolism. It is known that significant amount
of adipocytes are derived from mesenchymal stem cells (MSCs) presented in bone marrow and adipose tissues. However,
the studies on anti-adipogenic effects of M. oleifera leaves extract on adipogenic differentiation of bone marrow derived
mesenchymal stem cells are still poorly characterized. The experiment was conducted to study the efficiency of MOL extract on
adipogenic differentiation of porcine bone marrow derived mesenchymal stem cells (pBM-MSCs). pBM-MSCs were isolated
and cultured in completed medium or adipogenic differentiation medium containing 0 (control group), 100, 200, and 300 µg/
ml ethanolic extract of MOL to explore the anti-adipogenic differentiation ability. The results of MOL extract supplementation
demonstrated that M. oleifera leaves extract inhibits the cytoplasmic lipid accumulation as well as adipogenic differentiation
of preadipocytes.
Biography
Kulisara Marupanthorn currently working at Rajamangala University of Technology, Thailand
kulisara.m@rmutsb.ac.thKulisara Marupanthorn, Agrotechnology 2017, 6:4(Suppl)
DOI: 10.4172/2168-9881-C1-028