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Addiction Therapy 2016
October 03-05, 2016
Volume 7, Issue 5(Suppl) J Addict Res Ther
ISSN:2155-6105 JART, an open access journal
conferenceseries .com
October 03-05, 2016 Atlanta, USA
5th International Conference and Exhibition on
Addiction Research & Therapy
Ni Fan, J Addict Res Ther 2016, 7:5(Suppl)
Serum cytokines levels and their correlations with the psychotic symptoms in chronic ketamine abusers
Ni Fan
Guangzhou Brain Hospital, China
Exposing to NMDAR receptor antagonists, ketamine, produces schizophrenia-like symptoms in humans and deteriorates
symptoms in schizophrenia patients. Meanwhile, schizophrenia is associated with alterations of cytokines in the immune
system. Serum cytokine levels in chronic human ketamine users were measured as compared to healthy subjects. The
correlations between the serum cytokines levels with the demographic, ketamine use characteristics and psychiatric symptoms
were assessed. Subjects who fulfilled the criteria of ketamine dependence and healthy control subjects were recruited. Serum
cytokine levels were measured using an enzyme-linked immunosorbent assay (ELISA). The psychiatric symptoms of the
ketamine abusers were assessed using the Positive and Negative Syndrome Scale (PANSS). Serum levels of cytokines were
altered in chronic ketamine abusers which may play a role in schizophrenia-like symptoms in chronic ketamine abusers.
Biography
Ni Fan, got her ph.D. from Louisiana State University Health Science Center at 2009 and continued her postdoc training at Yale University School of Medicine from
2009 to 2012. Currently she is the vice director of the neuropsychiatric research institute of Guangzhou Brain Hospital, the Affiliated Brain Hospital of Guangzhou
Medical University. Her research was funded by National Nature Science foundation of China.