13 / 14
Page 43
Notes:
conferenceseries
.com
Volume 9
Journal of Addiction Research & Therapy
Addiction 2018
November 12-13, 2018
November 12-13, 2018 Dubai, UAE
9
th
International Conference on
Addiction & Psychiatry
Polysomnographic survey of sleep architecture in patients with Methamphetamine dependency in
early full remission phase
Zahra Amjadi Goojgi
Mashhad University of Medical Sciences, Iran
Introduction:
Nowadays, the association of stimulants and sleep disorders is more interested. Given the few number of studies
in the current scientific literature regarding assessment of the structure of sleep in patients with dependence on amphetamines,
especially after long periods of abstinence, present study is designed for the assessment.
Method:
This study was conducted in 2013-2014 in Mashhad and the subjects were selected through the convenience sampling
method from medium-term residential treatment centers. They were assessed through psychiatric interview whether or not
meet the inclusion/exclusion criteria. The case group consisted of 12 patients whom were diagnosed as in early full remission
according to DSM-IV TR criteria, were explained about how polysomnography worked and sent to sleep lab. The collected data
was analyzed by SPSS. On the basis of Kolmogorov-Smirnov results, the quantitative data with normal distribution were then
analyzed with t-test and the qualitative data with Chi-square test.
Result:
However the mean Total Sleep Period (TSP) and Total Sleep Time (TST) were in the normal range (403.0±52.9 and
333.6±79.1 minutes, respectively), there was a significant difference between these two variables (p=0.001). There was a slight
increase in Sleep Onset Latency (SOL) that was not significant (p=0.47). The participants generally, suffered poor quality of
sleep, subsequent to significant decrease of Sleep Efficiency (SE) (p=0.047) and slight rise inWASO (Waking After Sleep Onset)
(69.53±3.4, p=0.08). Besides, results indicated changes in sleep stages including significant rise in stages 1and 3 of non-REM
sleep with a trivial fall in NREM stage 2, though the total amount of NREM sleep was not significantly changed. Evaluation of
REM phase, in turn showed an increase in latency and percent of it significant. Although REM pressure which was calculated
by the number of REM episodes, slightly increased.
Conclusion:
Current findings shown sleep disturbances due to stimulants, within prolonged period of abstinence, could reflect
the preliminary mechanisms causing neuropsychiatric disorders, although it needs further studies which consider and resolve
our limitation.
Biography
Zahra Amjadi Goojgi has completed her Doctorate degree in Medicine from Islamic Azad University of Iran and Specialty degree of Psychiatry from Mashhad
University of Medical Sciences.
goojgi.zara@gmail.comZahra Amjadi Goojgi, J Addict Res Ther 2018, Volume 9
DOI: 10.4172/2155-6105-C3-042