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Volume 4, Issue 4(Suppl)

J Infect Dis Ther 2016

ISSN: 2332-0877, JIDT an open access journal

Infectious Diseases 2016

August 24-26, 2016

Page 51

Notes:

conference

series

.com

August 24-26, 2016 Philadelphia, USA

&

Infectious Diseases

Joint Event on

2

nd

World Congress on

Pediatric Care & Pediatric Infectious Diseases

International Conference on

Glenn S Tillotson, J Infect Dis Ther 2016, 4:4(Suppl)

http://dx.doi.org/10.4172/2332-0877.C1.007

Globalization of the unmet need of new antibiotics

B

acterial resistance to antibiotics is an escalating problem. There are significant efforts expanded in the battle to combat

this problem. Recent infectious diseases have hit the media especially viral infections such as Ebola, Zika and currently

Yellow Fever. The dissemination of these infections is especially worrying but we seem to have played down the bacterial

diseases. However, with increasing travel and the growing crisis of refugees it is obvious that the transfer of resistant bacterial

infections is highly likely or under-appreciated. Recent examples include azithromycin resistant

Shigella sonnei

infections;

NDM-1

Klebsiella pneumoniae

and other pathogens were from overseas. Additionally resistant infections may transfer within

a country where there may be marked susceptibility differences. So what may be the implications of this situation? Companies

both small and large are developing antibiotics to combat this issue are faced with multiple regulatory processes. These can

be challenging both in terms of completion and in terms of costs. As these issues become more global, there needs to be a

mechanism by which a streamlined development process applied so each country or region does not need to repeat or require

their own unique evaluations to approve a new antibiotic. The clock is ticking and we are running out of options and as we

travel more this can only get worse.

Biography

Glenn S Tillotson has over 30 years pharmaceutical experience in pre-clinical and clinical research, commercialization, medical affairs, scientific communications

including publication planning strategic drug development, life cycle management and global launch programs. He has been instrumental in the development and

launch of ciprofloxacin, moxifloxacin, gemifloxacin, fidaxomicin and several other agents. He is a SVP of Medical Affairs where he is preparing for the launch of

solithromycin for community acquired bacterial pneumonia. He has published more than 170 peer-reviewed manuscripts and is on several journal Editorial Advisory

Boards including the

Lancet Infectious Disease, eBioMedicine, Expert Reviews in Anti-infective Therapy

and

F1000.

gtillotson@cempra.com

Glenn S Tillotson

Cempra Pharmaceuticals, USA