Otolaryngology: Open Access
Open Access

Abstract

Leukoplakia of larynx has remained a debatable topic in laryngeal pathology for decades as per classification, histology and treatment is concerned. Smoking and alcohol are the major causes and there is sufficient evidence implicating gastroesophageal reflux and human papilloma virus in its pathogenesis. A wide range of therapeutic strategies are available for different grades of dysplasia. Despite this, a significant proportion of patients progress to carcinoma for which the patients with dysplasia need to be kept in regular follow-up. It is indispensable to subject leukoplakia to histopathological examination due to its nonspecific clinical polymorphism that may represent a wide range of epithelial changes in the laryngeal mucosa. It is, therefore, essential to subject these lesions to histological analysis to determine their biological nature. We discuss what to do with leukoplakias, nWe reviewed the clinical charts of 94 patients diagnosed with vocal cord leukoplakia treated in our service from January 2009 to January 2019. We discussed the histopathological diagnoses and the therapeutic approach.

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