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Periodontitis is an infectious disease that causes destruction of
the tooth attachment apparatus. Untreated periodontitis results
in progressive attachment loss that may eventually lead to
early tooth loss. There are a broad range of treatment options
available, but only some may be regarded as truly regenerative
procedures. Regeneration is deï¬ned as the reproduction or
reconstitution of a lost or injured part of the body in such a way
that the architecture and function of the lost or injured tissues are
completely restored. The aim of regenerative periodontal therapy
is to restore the structure and function of the periodontium.
Periodontal regeneration requires an orchestrated sequence of
biologic events, such as cell migration, adherence, growth, and
differentiation, to have the potential to increase the success and
predictability of periodontal regenerative procedures. According
to a position paper from the American Academy of Periodontology,
periodontal regenerative procedures include soft tissue
grafts, bone replacement grafts, root biomodiï¬cations, guided
tissue regeneration (GTR), and combinations thereof for osseous,
furcation, and recession defects. For many years, research has
attempted to use biologically active molecules to achieve periodontal
regeneration
A convenient technique to obtain a high concentration of PDGFs
is by preparing autologous leucocytes-platelet rich fibrin (L-PRP).
In basic terms, it involves the sequestration and concentration of
platelets in plasma, with subsequent application of this preparation
to wound-healing sites. It has been shown that application of
L- PRP to the wound-healing site increases the concentration of
platelets (and theoretically of PDGF) by up to 338%.
It was also speculated that, because of its ï¬brinogen content, L-PRP reacts with thrombin and induces ï¬brin clot formation,
which, in turn, is capable of upregulating collagen synthesis in
the extracellular matrix and provides a favorable scaffold for
cellular migration and adhesion. Various studies have reported
on the use of PRP in the treatment of periodontal intrabony defects
(IBDs) either alone or in combination with grafts or in the
treatment of furcation defects.
Biography
Dr.Aiman Obeid has completed his specialization in orthodontic in 2012 in Belarussian Medical State University, Belarus. After that he started his work as an orthodontist in UAE, he published his sientific work (about self ligating braces) in one of reputed medical journals, translated a research of 140 pages in lingual braces. Participated as a speaker in “2nd International Conference on Dental Practice” (webinar) about “AN EASY WAY TO BRACES SYSTME”. Spoke in TV interviews in famous local and international TV channel.
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