Clinical Pharmacology & Biopharmaceutics
Open Access

Abstract

The turnaround of the millennium brought us lots of expectation in terms of world market globalization economy, planet environment preservation and energy resources to mention a few. However, one of the most important discoveries in the science  eld was the unveiling of the human genome. Since then, most of the attention has turned to understanding the function of many genes and genomic fragments and their relationship with human pathophysiology. Much has been accomplished so far, such as BRCA1 and BRCA2 markers for breast cancer; HOXB13 gene for prostate cancer; APOE 4 for Alzheimer�s disease and many others that lead to the possibility of genetic testing to predict the risk of developing the disease, if the mutant variant gene is expressed in the individual genome. Co ee is the mostly widely consumed beverage worldwide with known health bene ts.  e genomic approach to search for speci c regions in the human DNA that are highly expressed within the co ee consumers is also a recent phenomenon. Genome-wide association studies (GWAS) have identi ed a number of regions of interest associated with co ee consumption. A consortium actually was created with the participation of researchers from all over the world, in an e ort to accelerate these  ndings.  e purpose is to understand the relationship between parts of the human DNA and the increased or decreased co ee use and its correlation with the prevention of a series of diseases as type-2 diabetes, cancers and neurodegenerative diseases that account for the majority of the chronic disorders that a ict our post-millennium population.

Biography

Santos has completed his PhD from SUNY at Buffalo and is an Associate Professor at Department of Pharmaceutical Sciences at School of Pharmacy. She has a company devoted to research and consultancy, Dr. Coffee in Savannah as well as a laboratory devoted to research on Coffee and health benefi ts. She has published many papers, participated as peer reviewer for various journals and has written chapters and textbooks in Portuguese, English and Korean.

Email: rsantos@southuniversity.edu