Journal of Clinical & Experimental Pathology
Open Access

Abstract

Hypercobalaminemia (high serum vitamin B12 levels) is a frequent and underestimated anomaly. The most obvious cause of an elevated vitamin B12 level is taking too much of the vitamin in the form of supplements. On the other hand, the etiological profile of high serum cobalamin predominantly encompasses severe disease entities for which early diagnosis is critical for prognosis. These entities are essentially comprised of solid neoplasms, hematological malignancies and liver and kidney disease. Vitamin B12 is generally not considered toxic in high levels, but it's important to determine if the elevation is due to excess vitamin supplements since other causes of a high vitamin B12 level are usually serious. This review reflects the potential importance of the vitamin B12 assay as an early diagnostic marker of these diseases.

Biography

Abdou Deyab is belongs to Egypt and comes with over 12 years of experience in the practice of Pediatrics Egypt. He has worked in various hospitals in Egypt where he held the position of Specialist Pediatrician.

E-mail: asd.pediatric@yahoo.com