Journal of Biotechnology & Biomaterials
Open Access

Abstract

In Belarus, genomic research is conducted in the following areas: Study on structural and functional organization of genomes; genetic engineering; development of genomic biotechnologies to improve breeding efficiency; DNA-diagnostics, prediction and monitoring of hereditary human diseases; sportsmen DNA-testing in sports. Transgenic potato resistant to Colorado potato beetle and other plant diseases were developed. Development of transgenic canola, flax, clover, cranberries and blueberries is being conducted. Transgenic goats with integrated human gene lactoferrin have being developed in collaboration with Russian scientists. The methods of marker-assisted selection were developed for 70 resistance and quality genes of 9 crops (potato, tomato, wheat, triticale, apple, rape, soya, barley, and flax) and for 25 resistance and quality genes of farm animals (cattle, pigs, and horses). Genetic certification system based on molecular marking were developed and tested for 10 agricultural crops. Genetic certification is used for verifying the origin of the pedigree cattle and pigs. The influence of genetic factors on the expression of such diseases as cardiovascular diseases, venous thromboses, diabetes, osteoporosis, rheumatoid arthritis, disturbances in normal physiological process of pregnancy, congenital or hypoacusis, mitochondrial pathologies and hemochromatosis was studied in Belarusian population. The relationship of combinations of gene polymorphic variants with predisposition to cancer is studied. Technologies for DNA-certification of sportsmen for a complex of basic genes exerting a great influence on the state of locomotor system, endurance, speed, force, hypoxia adaptation and ability to recover after physical efforts were worked out. The National DNA Bank of humans, animals, plants and microorganisms was established.

Biography

Email: kilchev@presidium.bas-net.by