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Objectives: To evaluate a new composite cartilage-perichondrium graft (button graft) for repair of small-sized tympanic
membrane perforations and to compare its success rate with that of the underlay and overlay techniques with temporal fascia or
tragal perichondrium.
Design: Prospective, sequential allocation of surgical technique study.
Setting: Tertiary care university hospital.
Patients: One hundred and ninety five (195) patients aged 14-42 years with central, uncomplicated tympanic membrane
perforations with completely visualized margins affecting less than 25% of the tympanic membrane, distributed in three groups:
1 (underlay), 2 (overlay) and 3 (button graft).
Interventions: Patients were allocated in sequence to: 1 underlay graft, 2 overlay graft and 3 cartilage tympanoplasty with button
graft technique. Patients were operated on under local anesthesia.
Main Outcome Measures: Postoperative status of the tympanic membrane, hearing improvement, duration of surgery and
incidence of complications at 12 months postoperative.
Results: Group-1 (underlay) had 66 patients; group-2 (overlay) had 65; and group-3 (cartilage) had 66. Success was defined
as the complete closure of the tympanic membrane one year after the operation. The success rates were 98.5% (65 of 66), 97%
(63 of 65) and 98.5% (65 of 66) cases and the mean air-bone gap gains were 10.18 (-5.4) dB, 8.5 (+6.5) dB and 9.1 (+5.1) dB
for groups-1, 2 and 3, respectively. No bone conduction threshold or speech discrimination score worsening was noted. The
mean durations of the operative procedure were 35-8.4 (range 22-63), 42-6.8 (range 33-75) and 23-6.3 (range 15-41) min for
groups-1, 2 and 3, respectively (P=0.02). Tympanic membrane retraction occurred in three cases in underlay group-1 and
tympanic membrane cholesteatoma pearls occurred in two cases in overlay group-2.
Conclusions: The button graft technique is an effective and fast alternative for the repair of small tympanic membrane
perforations if complete visualization of the margin is possible. The shorter time taken with the button grafts is mainly due to the
non-requirement for a skin incision. The results are comparable to those of the underlay and overlay techniques.