Journal of Biotechnology & Biomaterials
Open Access

Abstract

Antibiotics are an important class of Pharmacological agents used for treating infections, which are a major cause of human morbidity and mortality. Although antibiotics were first isolated from fungi and bacteria (natural Source), but over the years more and more synthetic antibiotics are flowing in market. During the last two decades, the development of drug resistance as well as the appearance of undesirable side effects of certain antibiotics has lead to the search of new antimicrobial agent. There is ample of documented evidence which show antibiotic properties in plant extracts. The present study is based on antibacterial and antifungal activity of wildly growing indigenous plants. Aqueous and ethanol extract of different part ( leaves, flower, fruit, root) of Oxalis amara, Argemone maxicana, Datura inoxia, Calatropis procera , Amranthus, Pithecellobium dulce, Ziziphus mauritiana, Croton bonplandianum, Cannibus sativa, Leucaena leucophela, Andographis Peniculata were taken for study, against pathogenic bacteria Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and fungus Candida albicans. Results were observed/ calculated by their zone of inhibition after 24 hours by agar plate gel diffusion method. These plants are showing their antibacterial and antifungal activities, differently for different microorganism. This laboratory experiments has shown that plant extracts are effective against a broad spectrum of microbes (Both Gram positive and Gram negative bacteria and fungus) & antibiotics from Plant extracts (Herbal antibiotics) are promising agents for developing newer antibiotics

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