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In Association with
Si- and Fe-substituted beta-tricalcium phosphate: Synthesis, characterization and in vitro properties
19th World Congress on Biotechnology
Kyung-Hyeon Yoo, Hyeonjin Kim, Youngjun Kim and Seog-Young Yoon
Pusan National University, South Korea
Posters & Accepted Abstracts: J Biotechnol Biomater
Abstract
The aim of this study was to investigate the effects of Si and Fe ions in �²-TCP on the physical and chemical properties. Betatricalcium phosphate (�²-TCP) has been known as biodegradable material for temporary medical devices. Enhancing the strength and osteoconduction properties of �²-TCP is important for their applications. To modify mechanical properties and in vitro behavior, Si and Fe ions were substituted in �²-TCP. The Si- and Fe- substituted �²-TCP powder were synthesized by co-precipitation method. Crystal structure and thermal properties of Si- and Fe-substituted �²-TCP were investigated by using X-ray diffraction combined with Rietveld refinement analysis and differential thermal analysis (DSC) to compare the effects of substituted elements on �²-TCP. Moreover, MTT assay, alkaline phosphate (ALP) staining confirmed the cytotoxicity, cell differentiation and cell proliferation.Biography
Kyung-Hyeon Yoo has completed her BS from Pusan National University.
