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Diabetes mellitus is a metabolic disorder of multiple aetiology characterized
by chronic hyperglycemia with disturbances of carbohydrate, fat and protein
metabolism resulting from defects in insulin secretion, its action or both. A diabetes
epidemic is underway. The number of people with diabetes is increasing due to
population growth, ageing, urbanization and increasing prevalence of obesity
and physical inactivity. Crude drugs of vegetable origin have been utilized for the
treatment of disease states, often of a chronic nature or to attain/maintain a condition
of improved health. Pharmaceutical preparations are made by extracting herbs with
various solvents to yield tinctures, extracts, fluid extracts or the like are known as
�phytomedicinals�. A large number of plants have been always used as folk herbs
and secret recipe for different illnesses and hypoglycemic herbs are widely used
as non-prescription treatment for diabetes. However, few herbal medicines have
been well characterized and demonstrated the efficacy in systematic clinical trials as
those of Western drugs. Some traditional medicines appear to be effective for both,
control of blood glucose and the modification of the course of diabetic complications
without side effects. Therefore, the present paper deals with diversity and distribution
area of 250 herbs from 113 families having hypoglycemic potentials, their traditional
and folk knowledge, phytochemical potentials, bioactive products and structures for
specific bioefficacies, comparable to standards with specific references. This paper
further briefly specifies the herbs and herbal combinations as hypoglycemic agents.
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