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The common denominator in pelvic floor dysfunctions is now recognized as being neuro-muscular. Neurophysiology is
assuming an ever increasing role in the diagnosis and management of pelvic floor disorders which may be caused by nerve
dysfunction, non-relaxing pelvic floor muscles or both. Urologic disorders and pelvic pain present an obvious relationship. The
majority of the urologic chronic pelvic pain syndromes arise from either a possible urinary bladder source known as interstitial
cystitis or prostate source known as prostate pain syndrome. Patients� evaluation should start with detailed history and
examination. Neurophysiological studies as urodynamics, manometry studies and electrodiagnosis (as EMG, pudendal nerve
conduction studies, sacral reflexes and evoked potentials) are helpful in assessing dysfunctions. Rehabilitation of pelvic floor
dysfunctions is individualized, depending on the specific etiology. Conservative therapies include behavior modification, pelvic
floor therapy, and biofeedback therapy, percutaneous stimulation of the posterior tibial nerve and myofascial release techniques
of trigger points. Botulinum toxin injection is effective in reducing urethral sphincter resistance or detrusor overactivity and
is used also in treating chronic obstructive constipation. Sacral neuromodulation can be used in the management of refractory
voiding dysfunction or selected cases of fecal incontinence.