Journal of Gastrointestinal & Digestive System
Open Access

Abstract

Cirrhotic patients who need critical care support show high morbidity and mortality rates compared with other critically ill patients. Their prognosis is influenced by both the severity of the underlying hepatic disease and the worsening of extra-hepatic organ function. Patients with cirrhosis are admitted at the Intensive Care Unit (ICU) for complications of portal hypertension culminating in multiple organ failure in a large portion of patients. The objective of the study is to identify predictors of mortality of patients with cirrhosis admitted to ICU of Cardinal Santos Medical Center and to compare these predictors to that established liver specific (Child-Pugh Score, MELD and MELD-Na) prognostic models. A total of 51 cirrhotic patients were admitted from June 1, 2009 to June 30, 2015. The results are presented as Mean � Standard Deviations and confidence intervals of 95% for quantitative variables and as percentages for categorical variables. It was found that hepatitis B is the most common cause of cirrhosis. Although Child-Pugh score indicates the severity of underlying liver disease, it cannot be considered as the best tool for predicting mortality. Among patients admitted at the ICU, encephalopathy is a complication involving low survival. Among the clinical parameters, the use of mechanical ventilator; the need for inotropic support; and the need for renal replacement therapy are associated with increased mortality. Among the laboratory parameters, lower venous pH and bicarbonate values are significantly associated with mortality. Hence, the prognosis for cirrhotic patients admitted to the ICU is poor.

Biography

Email: kenji.sato07@gmail.com