Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Google Scholar citation report
Citations : 3314
Journal of Biotechnology & Biomaterials received 3314 citations as per Google Scholar report
Indexed In
- Index Copernicus
- Google Scholar
- Sherpa Romeo
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- ResearchBible
- China National Knowledge Infrastructure (CNKI)
- Access to Global Online Research in Agriculture (AGORA)
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- ICMJE
Useful Links
Recommended Journals
Related Subjects
Share This Page
In Association with
Novel resorbable and osteoconductive nurse�A phase-silicocarnotite scaffold induced bone formation
2nd Annual Conference and Expo on BIOMATERIALS
Mazon P, Ros-Tarraga P, Meseguer-Olmo L, Rodriguez M A, and De Aza P N
Universidad Cat�³lica San Antonio de Murcia, Spain Instituto de Cer�¡mica y Vidrio, Spain Universidad Miguel Hern�¡ndez Avda, Spain Universidad Miguel Hern�¡ndez, Spain
Posters & Accepted Abstracts: J Biotechnol Biomater
Abstract
Alternatives to natural bone grafts are needed in a society that progressively prolonged life expectancy, and it should address the health problems of an aging population. In this context calcium silicophosphate scaffolds are promising candidates. Composition belongs to subsystem Nurseâ��s A-phase-Silicocarnotite was selected for the ceramic scaffolds that were prepared by the polymer replication method. An interconnected porous structure with a striking similarity to human cancellous bone tissue was obtained. Response to ceramic scaffolds was evaluated by implantation in New Zealand tibia rabbits in periods of 3 and 6 months. Radiological studies showed correct integration and partial resorption of the scaffold. Histological results presented no evidence for inflammation or infection at the implantation sites. Colonization process of the scaffold started in the periphery and then penetrated throughout implant porosity. Scaffolds degraded over time and that degradation happened according to the tissue in-growth rate. Histomorphometric analysis gave high BIC values (67.30% �± 1.41) opposite to control samples, where newly formed bone in the cortical defect increased in a smaller amount than in the grafted defects. After six months of implantation SEM studies reveal that the whole ceramic implant surface was covered by a newly formed bone tissue. The new bone layer was composed of Ca-P, mainly with traces of Si due to the gradual diffusion of Si ions from the scaffolds into the newly forming bone, which formed part of the biomaterialâ��s resorption process. The results indicate that this material provides an optimal microenvironment for the osteogenic differentiation of the undifferentiated osteoblastic precursor cells contained in hematopoietic bone marrow.Biography
Patricia Mazón studied Chemistry at the University of Alicante, and pursued her PhD about aminoacids synthesis. She started her adventure in Biomaterials field in 2012 at the University Miguel Hernández. Currently, she is a Professor at the Department of Materials Science, Optic and Electronic Technology and Researcher at the Biomaterials area of Bioengineering Institute.
Email: pmazon@umh.es
