Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Google Scholar citation report
Citations : 1529
Journal of Infectious Diseases & Therapy received 1529 citations as per Google Scholar report
Indexed In
- Index Copernicus
- Google Scholar
- Open J Gate
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- Euro Pub
- ICMJE
Useful Links
Recommended Journals
Related Subjects
Share This Page
Molecular analysis of influenza A/H3N2 and A/H1N1pdm viruses circulating in the Democratic Republic of Congo, 2014
2nd International Conference on Influenza
Edith Nkwembe, Roxana Cintron, Wendy Sessions, Hugo Kavunga, Pelagie Babakazo, Leonie Manya and Jean Jacques Muyembe
Institut National de recherches Biom�©dicales, DR Congo CDC Atlanta, USA Battelle Memorial Institute, USA Ecole de Sant�© Publique de lâ��UNIKIN, DR Congo Direction de la Lutte contre la Maladie, Senegal Centers for D
Posters & Accepted Abstracts: J Infect Dis Ther
Abstract
Introduction & Aim: Influenza is a common human respiratory infection and a cause of high morbidity and mortality. However, not much is known about influenza viruses circulating in Democratic Republic of Congo (DRC). This study aimed to characterize genetically and antigenically those strains affecting patients in this particular country. Methods: Nasal, throat and nasopharyngeal swabs from patients presenting with severe acute respiratory infections (SARI) or influenza-like-illness (ILI) were collected from August to December, 2014 in various surveillance sites selected in DRC and delivered to the National Institute of Biomedical Research (INRB) using the viral transport medium for molecular work. Viral RNA extraction and amplification by reverse transcription polymerase chain reaction (RT-PCR) were done and positive influenza samples with a Cycle threshold (Ct<30) were sent to the World Health Organization (WHO) Collaborating Center for Surveillance, Epidemiology and Control of Influenza at the US Centers for Disease Control and Prevention (CDC) in Atlanta for further genetic and antigenic characterization. Results: A total of 32 samples were tested at INRB and were found to be positive to influenza A with Ct<30. These samples were shipped to the US CDC in Atlanta for further sub-typing: 26 samples were influenza A (H3N2), 2 were influenza A (H1N1) pdm09, two samples were negative for influenza by RT-PCR and two samples contained insufficient volume for testing. The majority of influenza A (H3N2) viruses tested from DRC was antigenically related to the A/Switzerland/9715293/2013 vaccine virus, while two influenza A (H1N1) pdm09 virus isolates were antigenically characterized as A/California/07/2009-like. All A (H3N2) and A (H1N1) pdm09 virus isolates characterized in this study from DRC were sensitive to oseltamivir and zanamivir. Conclusion: Two genetically distinct influenza subtypes, A (H3N2) and A (H1N1) pdm09, were found to be circulating in the DRC during the study period. Based on these results, effective measures against influenza should be advised, including prevention of infection by either vaccination or administration of antiviral drugs prophylactically or therapeutically.Biography
Email: edithnkwembe1@gmail.com
