Journal of Gastrointestinal & Digestive System
Open Access

Abstract

Peyronie's disease is a fibrotic disorder of the tunica albuginea of the penis resulting in varying degrees of penile curvature and sexual dysfunction. Diagnosis of the disorder is made by detailed sexual history and focused physical examination. A wide range of medical treatments has been employed to treat the disorder. Medical treatment as Verapamil and some evidence exists to support the use of colchicine, potaba, L-carnitine and liposomal superoxide dismutase. The surgical treatment of Peyronie's disease is a viable and recommended alternative for men with compromised sexual function due to severe curvature or lesions causing penile instability. The use of Ultrasound session is one of the alternative choice of corrective procedure and should be tailored to each patient after a detailed evaluation of disease severity and sexual function Objective: To investigate epidemiological and clinical features of Peyronie's disease in an unselected group of patients who visit Urology Clinic for sexual problem not related to Peyronie?s disease and the outcome of ultrasound session as a noninvasive treatment for Peyronie?s disease. Patients & Methods: A series of 720 consecutive cases with sexual complaints was evaluated regarding to the age at diagnosis, the presence of general diseases, and the outcome of ultrasound sessions as a line of treatment on the improvement of the disease. The medical history which could be possibly related with the onset of the disease was investigated as well. The effect of ultrasound therapeutic session was assessed. We use plaque size, penile curvature, penile pain, erectile function, and patient satisfaction as points of treatment evaluation. Results: 148 patients (20.56%) had Peyronie?s disease (PD). Age of our patients ranged from 33 to 77 years old with Mean 43.97, DM presents in 147 patients (20.42%) while HTN presents in 111 patients (15.42%). Penile trauma was observed in 34/148 patients (22.9%). Ultrasound sessions was scheduled for all patients, 6/148 patients (4.0%) discontinue therapy, 37/148 patients (25%) had good improvement, 69/148 patients (46.62%) had weak response, 33/148 patients (22.29%) had no response Conclusions: The mean age of patients at diagnosis, the site of penile scars, and the outcome of ultrasound sessions could reach the satisfactory response. Thus, due to the diminution of pain spontaneously or after treatment, the patients with Peyronie's disease may have a normal life with satisfactory sexual function.

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