Breast Cancer: Current Research
Open Access

Abstract

Sarcoma of the breast is a rare condition. The biological differences from other primary breast tumours necessitate a corresponding difference in approach to diagnostic and management strategies. The rarity of the condition has made clinicopathological study difficult. We report a case of primary leiomyosarcoma in a 40-yr-old-female, with a 15Ã?Â?9 cm bosselated swelling, involving all four quadrants of the left breast. Her clinical features, sonography and trucut biopsy were compatible with cystosarcoma phyllodes and she underwent a left mastectomy for the same. Later, the histological and imunohistochemical studies established the diagnosis of leiomyosarcoma Grade 2 (strongly positive for vimentin, SMA and focally positive for beta-catenin). Given the differential for such a presentation, we emphasize the workup for a patient presenting with similar characteristics should be thorough. Following a simple excision with free margins, a histology examination with the appropriate immunohistochemistry is indispensable for an accurate diagnosis.

Biography

Ashwini Kannamma K has completed her MBBS from Mahatma Gandhi Medical College, and is doing her Master of Surgery from Sri Ramachandra Medical College, India.