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Background & Aim: Weight recidivism after Roux-en-Y gastric bypass (RYGB) is a common problem. Often, this weight loss failure
or regain may be due to a wide gastrojejunostomy (GJ). We evaluated the feasibility and safety of a novel approach of laparoscopic
wedge resection of gastrojejunostomy (LWGJ) for a wide stoma after RYGB associated with weight recidivism.
Methods: This is a single-center retrospective study of a prospectively-collected database. We analyzed outcomes of patients with
weight recidivism after RYGB and a documented wide GJ (>2 cm) on imaging, who underwent LWGJ between 11/2013-05/2016.
Results: Nine patients underwent LWGJ for dilated stomas. All patients were female with a mean�±SD age of 53�±7 years. Mean interval
between RYGB and LWGJ was 9�±3 years. All cases were performed laparoscopically with no conversions. Mean operative time and
hospital stay were 86�±9 minutes and 1.2�±0.4 days, respectively. The median (IQR) follow-up time was 14 (12-18) months. During
follow-up, there were no deaths, postoperative complications or unplanned readmissions or reoperations. The mean and median
(IQR) BMI before RYGB and LWGJ were 55.4�±8.1 kg/m2 and 56.1 (47.9-61.7) and 43.4�±8.6 kg/m2 and 42.1 (38.3-47.1), respectively.
One year after LWGJ, mean and median (IQR) BMI significantly decreased to 34.9�±7.3 kg/m2 and 33.3 (31.7-35.0) corresponding to
a mean %EWL of 64.6�±19.9 (P<0.05).
Conclusion: LWGJ is safe and can lead to further weight loss in patients experiencing weight recidivism after RYGB with a wide
GJ (>2 cm). Long-term follow-up is needed to determine the efficacy and durability of LWGJ and compare its outcomes with other
endoscopic/surgical approaches for weight recidivism after RYGB with a documented wide GJ.