Journal of Biotechnology & Biomaterials
Open Access

Abstract

The coordination chemistry of transition metal complexes with azomethine ligands has been widely studied, partly due to the use of such compounds as antibacterial drugs in the field of medicine. In particular, titanium (IV), platinum (II) and silver (I) complexes have been used in the treatment of numerous diseases. The aim of this work was to investigate the antibacterial and antifungal activities of new Pt(II) complexes. Four new Pt(II) complexes have been examined for antibacterial activity against pathogenic strains Listeria monocytogenes 4b ATCC19115, Staphylococcus aureus ATCC25923, Escherichia coli ATCC1280, Salmonella typhi H NCTC 901.8394, Brucellaabortus RSKK03026, Staphylococcus epidermis sp., Micrococcus luteus ATCC93419, and Shigelladysenteriatyp 10 NCTC 9351, and antifungal activity against Candida albicans Y-1200-NIH, Tokyo. The antimicrobial test results of Pt(II) complexes including chloride ion in coordination sphere exhibited better activity than some known antibiotics.

Biography

Hatice Öğütcü is Associate Professor of Microbiology at Ahi Evran University, Turkey. She obtained her undergraduate degree in Biology in 1991 at Atatürk University. She graduated in Biology at Atatürk University. She attained the Doctoral degree in Microbiology in 2000.