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In Association with
In deep transcriptomic analysis using RNA-seqto identify the growth and immunity related differentially-expressed genes in fat, liver and muscle tissues of one day piglet and adult Berkshire porcine
8th Euro Biotechnology Congress
Mrinmoy Ghosh and Dong Kee Jeong
Jeju National University, Republic of Korea
Posters-Accepted Abstracts: Biotechnol Biomater
Abstract
Mainly in Asia, East Asia and Europe, the pig is an important livestock animal and a major source of meat-based protein. It was reported that Berkshire pigs are hardy, have good mothering capabilities and immunity resistanceperform very well outdoors considered extreme of modern Western pig breed. Taken collectively, our approach integrating, massively unbiased information on the differential expressed genes in the fat, liver and muscle tissues RNA-seq technique was used to investigate the transcriptomes via an illumina and mapped to the pig genome using Tophat2.Using differential expression analysis, we further identified a number of genes up-regulated inthree samples from piglets and adult Berkshire.Moreover we found that 46% of muscle, 28% of fat and 54% of liver genes suppressexpressed in piglets than adult Berkshire. Gene Ontology and signaling pathways showed the higher immune response in piglets while the lipid metabolisms significantly (P<0.01) was commonly enriched pathways in all three tissuesof adult Berkshire. We identified candidate genes involved various biological functions in piglet and adult phase of Berkshire. Our findings provide a new perspective for understanding the expression different of candidate genes in piglet and adult phase in Berkshire and revealed successful marker-assisted selection formeat quality; body growth andimmune genes conferring an advantage to disease resistance and growth performanceare beneficial to breeding aiming to improvement of livestock productivity.Biography
MrinmoyGhosh has completed his PhD at the age of 28 years from AcharyaNagarjuna University and pursuing his Postdoctoral studies from Jeju National Univeristy, South Korea.Theprinciple research interest biostatistics, system and structural biology includes recognition of differentially expressed genes in mammalian groupand understanding the biodiversity, molecular evolution of marine microbial world.As a Postdoctoral Fellow, he is working on the next generation sequencing analysis covering the relevant candidate genes and SNPs. He has published more than 30 papers in reputed journals.
Email: mringhs2010@gmail.com
