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Pattern of breast diseases in Yemen is inadequately studied; we studied the histopathological breast diseases in order to find
out the histopathological pattern in patients suffering from breast diseases in Modern Histology Lab, Aden, Yemen. We
performed a retrospective and prospective study conducted at Private Modern Histology Lab, Aden, Yemen during the period
from January 2005 to December 2008. The data were collected from the referral sheets. A total of 286 biopsies cases of breast
diseases 275 (96.2%) were female and 11 (3.8%) were man. In female Benign breast tumor was the most common lesion found
is comprising 32.4% in age group between 20-29 years, followed by fibrocystic changes 28.4%, inflammatory lesion 15.3%
and accessory breast 4.3%, while malignant cases 19.6% with an incidence pike between 50-59 years (53.8%). Invasive ductal
carcinoma 39 (72.1%) was the more common breast carcinoma founded, the tumor size between 2 to 5 cm (56.4%). 35.2%
of female had metastasis in axillary nodes, in conclusion the female gender affected by breast diseases more than men with
predominance of benign conditions over malignant lesions in both sex. To allocate a special budget for future researches in
breast cancer including campaign against breast cancer and raising the awareness of the public about digital pathology breast
cancer through mass media, the quality of the histopathological laboratories should be improved by introducing modern
techniques for better assessment of surgical pathology specimen. It is important for pathologists, radiologists, to be aware of or
try to detect or search for DCIS or LCIS in benign breast tumor.