Journal of Clinical & Experimental Pathology
Open Access

Abstract

Objective: The objective of the study was to determine the frequency and pattern of non Hodgkinâ??s lymphoma (NHL) in adults in a tertiary care hospital. Material & Methods: This retrospective study was conducted at Histopathology Department, Dr. Ziauddin Hospital over a period of 09 years, from 2005 to 2013. 192 cases of Non Hodgkinâ??s lymphoma (NHL) were retrieved from surgical pathology record. After routine H & E stain examination, a panel of immunohistochemical stains was applied on formalin fixed paraffin embedded tissue. The data was analyzed for type of lymphoma, age & sex distribution, site of biopsy and immunophenotypic features. Results: Out of 192 cases of non Hodgkinâ??s lymphoma (NHL), 132 (69%) were males & 60 (31%) were females. Mean age of patients was 46.7 years and median age was 47 years. B cell lymphoma was out numbered (87%) than T cell lymphoma (13%). Diffuse large B-Cell lymphoma was the commonest (113) B cell lymphoma followed by other types of lymphoma. 52% cases were from extra nodal sites followed by 34% of nodal lymphoma. Site of biopsy was not mentioned in 14% cases. Conclusion: In adults, B cell lymphoma is more frequent than T cell lymphoma with diffuse large B-cell lymphoma being the commonest non Hodgkinâ??s lymphoma.

Biography

Uzma Bukhari has completed MBBS from Liaquat University of Medical and Health Sciences Jamshoro. She has completed MPhil histopathology from Karachi University Pakistan. She has been completed residency in FCPS (Fellow of college of physician and surgeon Pakistan) from Dr. Ziauddin hospital Karachi and going to appear in exam this year. Currently she is working in histopathology clinical laboratory of Dr. Ziauddin hospital. She has published 10 research papers and one paper has been published internationally.