Journal of Biotechnology & Biomaterials
Open Access

Abstract

The use of bacteria in the synthesis of nanoparticles emerges as an eco-friendly and exciting approach for production of nanoparticles due to its low energy requirement, environmental compatibility reduced costs of manufacture, scalability and nanoparticles stabilization compared with the chemical synthesis. The production of gold nanoparticles by the Bacillus lichniformis GPI-2 was reported in this study. Cells exposed to Au3+ turned from colorless into an intense purple color. This change of color indicates the accumulation of extracellular gold nanoparticles. Elemental analysis of particles composition was verified using TEM analysis. The gold nanoparticles sizes were verified by TEM showing different types of particles of predominant spherical shape with size ranging from 20-51 nm. FT-IR was utilized to characterize the chemical surface of gold nanoparticles. This assay supports the idea of a protein type of compound on the surface of biosynthesized gold nanoparticles. Gold nanoparticles (AuNPs) provide non-toxic carriers for drug and gene delivery applications. Gold nanoparticles have been used as anti HIV, anti-angiogensis, anti-malarial and anti-arthritic agent. Furthermore, gold nanoparticles are used for delivering molecules into cells to slow down cancer cells. This green route of biosynthesis of GNPs is simple, economically viable and eco-friendly process.

Biography

Email: rajnithakur136@yahoo.in