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Statement of the Problem
Diarrheal diseases are responsible for a significant amount of
children deaths. Although, rotavirus is recognized as a major cause
for pediatric diarrhea, but the role of other viruses especially
norovirus is still unrecognized for the Pakistani population. Norovirus
is very contagious and can affect a vast range of species ranging
from cattle, pigs, dogs, mice, cats, sheep, lions to humans. In humans
it causes vomiting and diarrhea and can affect the people of all
ages but mainly the children with less than five years of age. There
is no significant data available regarding the prevalence and
genetic variability of norovirus in Pakistan.
Method
This study was based on hospital surveillance, from December 2019
to September 2020 for the detection of noroviruses in children of
less than five years of age. Total 100 samples were collected with
predesigned questionnaire to assess the risk factors and clinical
characteristics related to noroviruses.
Conclusion & Significance
Total 15% samples were detected positive by the confirmation of
RT-PCR for genogroup GII (G2SK) which is most prevalent. From all
the risk factors including age, gender, vomiting, fever, type of milk,
water and meal consumption, habit of hand, vegetables and fruits
washing; only the contact of patient with an acute gastroenteritis
patient was found significant. The remarkable cases of childhood
diarrhea associated with noroviruses calls for the large-scale
epidemiological surveys to calculate the burden of noroviruses and
assess the risk factors. As it is a food borne pathogen so there
is also a need to follow the strict hygienic measures during the
processing of food items.
Recent Publications
Ahmed, T., Hussain, S., Rinchen, S., Yasir, A., Ahmed,
S., Khan, W. A., ... & Ricketson, R. (2020). Knowledge, attitude and
practice (KAP) survey of canine rabies in Khyber Pakhtunkhwa and
Punjab Province of Pakistan. BMC public health, 20(1), 1-12.
Biography
Ammar Yasir is working as a research associate in the Department of Epidemiology and Public Health, at the University of Veterinary and Animal Sciences, Pakistan. Recently, he has also completed his MPhil Degree in the same department.
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