Journal of Biotechnology & Biomaterials
Open Access

Abstract

This study were performed to the cosmeceutical activities of compare to steamed Codonopsis lanceolata and just Codonopsis laceolata: Codonopsis lanceolata extracted by 70% ethanol extraction at 60 (SCE1), extracts of three-times steaming process and 70% ethanol extraction at 60 (SCE3), extracts of five-times steaming process and 70% ethanol extraction at 60 (SCE5) and extracts by 70% ethanol extraction at 60 (CE),.The highest extraction yield was measured as 25.2% for extracts of five-times steaming process, whose value was very close to 24.4% from once steaming process .DPPH free radical scavenging activity of the extracts from five-times steaming process showed high ratio as 74.68%,followed by 52.02, 61.42 and 63.34(%) from ethanol extraction at 60 (CE), extracts of once steaming process and 70% ethanol extraction at 60 (SCE1), extracts of three-times steaming process and 70% ethanol extraction at 60 (SCE3), respectively. The lowest cytotoxicity against from fibroblast cell line, CCD-986sk was observed in adding 1 mg/mL of the extracts from five-times steaming process. The extracts from both five-times steaming process and ethyl alcohol extraction effectively reduced the expression of MMP-1 on UV-irradiated human fibroblast CCD-986sk cells as 44.3% and was showed hightyrosinase inhibitory potency as 66.8%. The other extracts show relatively low activities in the range of 36~54(%). From these results, we concluded that the extracts of Codonopsis lanceolata could be used for anti-aging and skin-whitening agent, and extracts from five-times steaming process should be a more efficient process than 70% ethanol extraction.

Biography

Woo Seok Choi attends the Department of Medical Biomaterials Engineering in Kangwon National University, Korea and he will graduate from in 2014. Now he is a student in Food & Bioprocess Engineering Lab in Kangwon National University and he apply for admission to the master?s course in Kangwon National University.