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Gastro-esophageal reflux disease (GERD) is a complex disorder resulting from multiple contributing factors, including acid
production, lower esophageal sphincter tone and location, and anatomic barriers to reflux created by the angle of His and the
diaphragmatic hiatus ,The high prevalence of (GERD) together with drug dependence , intolerance and side effects was the driving
force for development of interventional procedures . The laparoscopic fundoplication was the only option for many years inspite being
unfavorable by the patients. The unchallenged practice released many reports of various types of complications and unwanted results.
That paved the way for emerging of less invasive trance-oral endoscopic procedures for (GERD). The three available competing
technics is Stretta . Esophyx and MUSE . Every procedure is evolved during the last years into new generations with more safety and
efficacy after many modifications in precision. Size and quality of tool .the decision to do endoscopic management and choosing
between the available procedures should be perfectly tailored to individual patients. The interpretation of symptomatology score and
Endoscopic findings together with high resolution manometry HRM and 24 hour impedance PH metry results decides the treatment
path for the patients. A major guidelines shift occurred in the last years towards endoscopic management of GERD .some limitations
have been set for such managements as the age and size of hiatus hernia, however defective esophageal clearance is not very much
an obstacle as in the case of Nissen fundoplication. Many factors affecting the contradicting outcome reports about efficacy of each
procedure, collecting subjective and objective measurements for every procedure will help for prioritization and sitting standards of
care for GERD, the procedures have financial obstacles towards wide range application for patients.