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Efficacy and mechanism of acupuncture on patients with chronic sciatica: Protocol for a randomized, patient-assessor blind, sham-controlled clinical trial
Joint Event on Global Summit on Traditional & Restorative Medicine & 10th World Congress on Neuropharmacology
Woo-Chul Shin,Mi-Yeon Song, Koh-Woon Kim,Eun-Mo Song and Jae-Heung Cho
Sciatica is a relatively frequent illness with a highest incidence of 40% and can easily
become a chronic and relapsing symptom. Although numerous systematic reviews have
compared various therapies for sciatica, the validity of their included studies is limited.
Considering the shortcomings of conventional treatment options for sciatica, acupuncture
could be a possible option. However, evidence supporting its efficacy and mechanism
is lacking. The aim of this study is to investigate the effect and neurophysiological
mechanism of acupuncture in patients with chronic sciatica. This ongoing study is a
randomized, patient-assessor blind, 2-arm parallel non-penetrating sham-controlled
clinical trial. Eligible participants, adults (19-70 years of age) with a clinical diagnosis
of chronic sciatica blinded to the treatment received, will be randomly allocated into the
real acupuncture treatment group (manual acupuncture plus electroacupuncture, n=34) or
the sham acupuncture control group (sham acupuncture plus placebo electroacupuncture
without electrical stimulation, n=34) and receive treatment two times a week for a total
of eight sessions over four weeks. Functional magnetic resonance imaging will be
implemented at baseline and endpoint to investigate the mechanism of acupuncture. The
primary outcome measure is VAS for bothersomeness. The secondary outcomes include
VAS for pain intensity, Oswestry Disability Index, EuroQol 5-Dimension, Coping Strategy
Questionnaire, Beck Depression Inventory, and State-Trait Anxiety Inventory. Adverse
events will be assessed at every visit. The results of this trial will provide important
clinical evidence for the effect of acupuncture and demonstrate how acupuncture can be
helpful for the treatment of chronic sciatica.
Biography
He has completed her PhD at the age of 30 years from Kyung Hee University and postdoctoral research fellow from Columbia University College of Physicians & Surgeons. He is now a professor of Kyung Hee University College of Korean Medicine. He has published more than 25 papers in reputed journals and has been serving as an editorial board member of the Journal of Korean Medicine Rehabilitation.