Journal of Obesity & Weight Loss Therapy
Open Access

Abstract

Obesity is a chronic disease that increases the risk for coronary heart disease (CHD) and type II diabetes (T2DM) and it’s a growing
public health problem worldwide. The purpose of our study was to develop a model of therapeutic efficiency high-intensity
lifestyle intervention intended for truncal obese adults with increased cardiometabolic risk. Within the randomized controlled trial
at a group of truncal obese adults with risk factors for CHD and T2DM, we suggest the following two types of high-intensity lifestyle
interventions: 1st-low fat, hyperprotein, restriction diet (RD) of 1200-kcal/d (female) and 1500-kcal/d (male) with low glycemic (GI)
and atherogenic index, and a specific proportion among SFA, MUFA and PUFA. The 2nd-RD and the individually dosed physical
activty (PA) with gradually, from low to moderate and peaks of high intensity (50%-60%-75% VO2 max) in accordance to the initial
level of the individual aerobic capacity (VO2 max), expressed into METs. After 30 days there was increase energetic value of RD for
200-kcal/d in accordance with increased PA. The changes in anthropometric measures, metabolic profiles, VO2 max and BMR are
evaluated after 30 and 50 days. The efficiency of the progammed PA in combination with RD represents a significant higher reduction
of BMI (kg/m2), WHR, fat mass index, risk factors for CHD and metabolic complication (hyperglycemia, dyslipidemia, arterial
hypertension and atherogenic indexes) associated with truncal obesity and significant improvement in cardiorespiratory fitness for
17.16% VO2 max from initial level.

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