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Effects of diabetes and depression on cognitive function in patients with Dementia: (Sadem study)
3rd International Conference on Alzheimers Disease & Dementia
Teresa Juarez-Cedill, Ging-Yuek R Hsiung, Amir A Sepehry, B Lynn Beattie, Rosalinda Sanchez-Arena, Carmen Garcia-Pena, Sergio Sanchez- Garcia and Claudia Jacova
National Medical CenterCentury, Mexico UBC Division of Neurology, Canada UBC Hospital, Canada UBC Divisions of Geriatric Medicine, Canada
ScientificTracks Abstracts: J Alzheimers Dis Parkinsonism
Abstract
Objective: We examine the patterns of cognitive functioning in individuals diagnosed with dementia, diabetes, and depression as compared with dementia plus diabetes, or dementia plus depression and healthy controls. Methods: 207 participants with dementia, 83 with Alzheimer�s disease, 66 vascular dementia and 58 mixed dementia were included. All subjects underwent global neuropsychological assessment via the Mini-Mental State Examination, and assessment for depressive symptoms via the Center for Epidemiologic Studies Depression Scale. Diabetes diagnoses were confirmed by the medical examination Results:A mixed-effects repeated measures analysis of covariance indicated a significant difference in cognitive functioning between the study groups. Our results showed that patients with diagnosis of dementia and depression showed greater cognitive dysfunction compared to controls, but to a lesser degree in patients with comorbid dementia diabetes. Conclusions: These results suggest that dementia, when combined with depression or diabetes mellitus, adversely affects cognitive performance.Biography
Email: teresa.juarez@imss.gob.mx
