Journal of Obesity & Weight Loss Therapy
Open Access

Abstract

Background: The incidence of acute pancreatitis (AP) is rising with increased prevalence of obesity, which exacerbates pancreatic injury. Metabolic syndrome (MS) is defined as a cluster condition of cardiovascular risk factors, including: hyperglycemia, dyslipidemia, hypertension, and central obesity. We analyze if the presence of obesity and/or MS affects the course of pancreatitis. Methods: Data were collected from 140 patients who were diagnosed with AP between January 2010 and February 2013. Anthropometric data, including body mass index (BMI) and waist circumference (WC), were measured. Biochemical tests were administered including fasting glucose, triglyceride, LDL and HDL cholesterol, and total cholesterol. Atlanta criteria, APACHEII, and Ranson�s were used to define severe AP. Patients were classified as having MS based on International Diabetic Federation (IDF) criteria. Results: The mean BMI was 30.15Kg/m2. 16 patients (11.4%) had severe AP, while 124 patients (88.6%) had mild AP. We found that 62.8% of AP patients fulfilled the criteria of MS (P value=0.000). Body weight can be used to predict clinical severity of AP with significant P value (P=0.009). Conclusions: The presence of MS in pancreatitis patients is noticeable, but it doesn�t affect the course of disease severity, while obesity correlates with pancreatitis severity.

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