Journal of Infectious Diseases & Therapy
Open Access

Abstract

Background: HIV/AIDS is one of major world public health issue, which continues to get people’s lives while new cases are
being infected each year. In 2013, 1.5 million people have died fromHIV and 2.5 million new infections have happened.People
with different demographic characteristics attend in blood donation, which creates an opportunity for estimation of HIV
frequency and its risk factors. We studied data on HIV infection of blood donors from 2011-2014, to estimate frequency of
HIV infection and some of its risk factors in Alborz province.
Materials and Methods: In a cross sectional design, data on all blood donors in Alborz province within 4 years from March
2011 to 2015 were studied. The blood transfusion organization registries used for data collection.During the study period,
People donated 202814 times in Alborz province. After deleting duplicates (repeated), 109817 people entered the study.Data
were described within 95% confidence interval and Chi square, Fisher exact test and logistic regression(backward Stepwise
-Wald) used for comparisons and calculating adjusted odds ratios.
Findings: During the study period, 109817 people donated blood. The mean age of donors was 35.8 (±9.94) years and most
of them (93.7%) were males. During these 4 years, 15 donors confirmed for HIV infection. The rate of infection was 13.66
in 100,000 populations. Rate of HIV infection in women (43.33 in 100,000) and men (11.66 in 100,000) was different (P
value<0.042). people who were graduated from high school or academic educations(7.91 in 100,000) had a lower rates than
people less than high school graduation( p<0.022).
Adjusted odds ratios indicate that female gender (adjusted OR=3.73, p< 0.042) and education level less than high school
graduation (adjusted OR=4.26, p< 0.009) increase the odds of HIV positivity in blood donors.
Conclusion: Rate of HIV infection in blood donors is low which reflects relatively lower rate of infection in our society and
cause more blood transfusion safety. Higher HIV infection frequencies in female donors, needs more attention. We don’t know
that this pattern can be seen in other regions of the country; but this may be a result of changing pattern of disease transmission
from Injecting drug use to heterosexual sex activities. We recommend a wider national research based on available data from
blood donation and/or designing studies to better estimate the frequency and its risk factors.

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