Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Google Scholar citation report
Citations : 2287

Journal of Obesity & Weight Loss Therapy received 2287 citations as per Google Scholar report

Journal of Obesity & Weight Loss Therapy peer review process verified at publons
Indexed In
  • Index Copernicus
  • Google Scholar
  • Open J Gate
  • Genamics JournalSeek
  • Centre for Agriculture and Biosciences International (CABI)
  • RefSeek
  • Hamdard University
  • EBSCO A-Z
  • OCLC- WorldCat
  • SWB online catalog
  • CABI full text
  • Cab direct
  • Publons
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • University of Bristol
  • Pubmed
  • ICMJE
Share This Page

Determination of plasma and leukocyte vitamin C concentrations in a randomized, double-blind, placebo-controlled trial with Ester-C®

7th Obesity & Endocrinology Specialists Congress

Susan Hazels Mitmesser

Stony Brook University, USA

ScientificTracks Abstracts: J Obes Weight Loss Ther

DOI: 10.4172/2165-7904.C1.039

Abstract
Rapid uptake of vitamin C into blood and retention in tissues are important indicators of the efficacy of vitamin C supplementation and its immune-supporting role. This double-blind, placebo-controlled, crossover study evaluated the bioavailability of vitamin C in plasma (reflective of recent intake) and leukocytes (reflective of tissue stores on immune function) from a novel vitamin C formulation, Ester-C���®. Thirty-six adults were randomized to receive placebo (PL, 0 mg vitamin C), ascorbic acid (AA, 1000 mg vitamin C) and Ester-C���® (EC, 1000 mg vitamin C). Plasma and leukocyte vitamin C were measured predose and at 2, 4, 8 and 24 hours postdose. The concentration and percent change from baseline in plasma were significantly higher with EC at all-time points when compared to PL. No significant differences between EC and AA were observed in plasma concentration. Plasma area under the curve (AUC0-24h) was higher for EC (P<0.001) compared to PL. The concentration change from baseline in leukocyte vitamin C was increased with EC at 24 h post-dose (P=0.036) while no significant within-group changes were observed in AA or PL at any time point. The percent change in leukocyte vitamin C concentration was higher for EC at 8 and 24 hours compared to AA (P=0.028 and P=0.034, respectively) and PL (P=0.042 and P=0.036, respectively). It is concluded that a single dose of EC resulted in favorable percent change in leukocyte vitamin C concentration compared to AA and PL, indicating EC is retained longer within leukocytes.
Biography

Susan Hazels Mitmesser completed a PhD in Nutritional Biochemistry from the University of Nebraska and a Master’s degree from the University of Nebraska Medical Center. She brings numerous years of industry experience and is an Adjunct Professor in the Department of Family Medicine at Stony Brook University. She has published in many peer-reviewed journals and is a contributing author for numerous book chapters relating to nutrition in adult and pediatric populations. She serves on the Editorial Board of four peer-reviewed journals and is an active member of the American Society of Nutrition, the American Association for the Advancement of Science and the New York Academy of Sciences. She serves on the Senior Scientific Advisory Council for the Council for Responsible Nutrition.

Email: susanmitmesser@nbty.com

Relevant Topics
Top