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Continuous intra-articular and periarticular of levobupivacaine for management of pain relief after total knee arthroplasty: A prospective randomized, double-blind pilot study
International Conference on Pain Research & Management
Alessandro Paglia
San Salvatore Hospital, Italy
Posters & Accepted Abstracts: J Pain Relief
Abstract
Background: Total knee arthroplasty (TKA) can result in major postoperative pain which can impact on the recovery and rehabilitation of patients and for this reason the use of a pain-control infusion pumps (PCIP) enhances analgesia for TKA. Purpose: To investigate whether a PCIP of levobupivacaine would reduce pain in patients following TKA. Methods: This was a prospective, randomized, controlled study conducted in 57 patients. Criteria for participation were unilateral TKA for osteoarthritis, and no allergies to levobupivacaine. The primary outcomes measured were postoperative pain intensity on visual analogue scale (VAS) score measured at 24 hours and 48 hours. Other measures included amount of narcotics, presence of adverse events and length of hospital stay. Results: PCIP-treated patients (n=28) showed significant reductions in VAS score at any time versus control (p<0.01). Amount of narcotics, presence of adverse events, length of hospital stay were significantly less with the PCIP versus control (each p<0.01). Conclusion: The use of a mix of levobupivacaine, ketorolac-trometamina and adrenalin provides a safe and effective means by post-operative pain relief in patients undergoing TKA. Level of Evidence: Level II therapeutic study.Biography
Email: a_paglia@live.it
