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Comparison of virological and serological findings on Moroccan bluetongue virus 1 and 4 infected sheep
3rd Euro-Global Conference on Infectious Diseases
Kamar Drif
Institut Agronomique et Veterinaire Hassan II, Morocco
Posters & Accepted Abstracts: J Infect Dis Ther
Abstract
The bluetongue (BT) virus has been reported in Morocco in 2004. To investigate the involvement of BTV 1 and BTV4 infections, on immunity of sheep and to provide a basis for interpretation of serological and virological data, experimental infections were conducted with BTV-1 and BTV-4 strains. Antibody responses to BTV infections were evaluated using two enzyme linked immunosorbent assays and microtiter serum neutralization tests (mSNTs) in addition to virological monitoring based on RT-PCR. Large variation was observed between the three groups in clinical signs, showed variation in immune responses between animals. Viremia for BT virus was readily detected in sheep following BTV-1 infection, but was not detected following exposure to BTV-4 in group B and C. The high manifestation of clinical signs caused by BTV1 serotype compared to those caused by BTV4 could likely be due to BTV strains antigenicity and could probably be responsible in suppressing or manifesting BT symptoms and viremia for this serotype.Biography
Email: drif.kamar@gmail.com
