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Comparison Of Some Cardiometabolic Risk Factors In Peri-urban Adolescent School Learners In Mthatha, South Africa | 40265
ISSN: 2165-7904
Journal of Obesity & Weight Loss Therapy
Open Access
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Background: Childhood and adolescent obesity is an important predictor of adult cardiometabolic diseases. Current data on ageand
gender-specific cardiometabolic risk factors are lacking in the peri-urban Eastern Cape Province, South Africa. However, such
information is important in designing innovative strategies to promote healthy living among children and adolescents. The purpose
of this pilot study was to compare and determine the extent of cardiometabolic risk factors between samples of lean and overweight/
obese adolescent population in a peri-urban community of South Africa.
Methods: In this cohort study, 13-17year old male and female adolescents participated in the study. Fasting venous blood samples
were obtained for total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C),
triglyceride (Trig), high sensitive C-reactive protein (hsCRP) and blood sugar. Anthropometric measurements included weight,
height, waist and hip circumferences. Body mass index was calculated. Blood pressure was measured; and metabolic syndrome was
assessed using appropriate diagnostic criteria for children and adolescents.
Results: All cardiometabolic risk factors were elevated in the overweight/obese learners compared with the lean: low HDL-C (RR =
2.21), elevated TC (RR = 1.23), elevated LDL-C (RR = 1.42), elevated Trig (RR = 1.73), and elevated hs-CRP (RR = 1.9). There were
significant atherosclerotic indices among the overweight/obese compared with the lean group: TC/HDL and LDL/HDL (2.99�?±0.91
vs 2.63�?±0.48; p=0.016 and 1.73�?±0.61 vs 1.41�?±0.46; p= 0.014, respectively). Of the 410 participants, 14.4% had no risk factor for the
metabolic syndrome (MS) 21.2% had MS. Participants with MS also had lower adiponectin and serum Mg2+ levels, higher hs-CRP.
On the other hand markers of atherosclerosis tended to be higher in males compared to females.
Conclusion: There are multiple cardiometabolic risk factors among the overweight/obese compared to lean adolescents in this study.
The high proportion of adolescents with MS indicates the importance of school health programs to focus on the promotion physical
exercise, healthy eating and keeping appropriate weight.