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Introduction: Pneumonia accounts for 15% all deaths in children under 5 years of age, being the single largest
infectious cause of deaths in children worldwide according to WHO. This study was conducted to study the clinical
spectrum of pneumonia. Establishing the exact etiological factor is a difficult task, as there are no definite clinical,
radiological markers to differentiate between causative organisms. Hence by detecting the genetic material of
causative organism by serum PCR and correlating it with the clinical and radiological features can help in appropriate
use with antibiotics.
Material and Methods: It is a observational study conducted in department of paediatrics KIMS hospital Bangalore,
India which included inpatients admitted with clinical and radiological features of pneumonia over a study period
from February 2018-July 2019. In this study we excluded Immunocompromised children and children on long term
steroids >6 months. After obtaining informed written consent, detailed history and clinical examination was done.
Investigations including complete hemogram, CXR were done. Under sterile precautions, Blood samples for serum
PCR and blood culture and sensitivity were obtained. Serum PCR was done for a panel of 33 respiratory pathogens.
Results: Etiological agents were identified in 62% (93/150) of cases. 39% caused by solely Streptococcus Pneumoniae
and an additional-13% coinfection of Streptococcus pneumoniae with other bacteria or viruses. In total 52% (78/150)
positive for Streptococcus pneumoniae. Staphylococcus aureus has been detected to be the second common organism
14% (21/150), 6% with Staphylococcus aureus as the sole causative agent and 8% as coinfection. Klebsiella pneumoniae
in 3% and Bordetella Pertussis in 3% cases. Viruses were identified in 3% (5/150).
Conclusion: In our study Pneumococci was identified in 52% of cases. In the study population most of them where
from the lower to middle socioeconomic status, with overcrowding, lack of proper hygiene, inadequate nutrition and
none of them had received vaccination against pneumococci.
Biography
Vivetha Elango has completed MBBS in the year 2016. She is pursuing her postgraduate in MD pediatrics at Kempegowda Institute of Medical Sciences Bangalore. This is currently the first paper that has been done.
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