Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.
Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers
Google Scholar citation report
Citations : 4454
Journal of Analytical & Bioanalytical Techniques peer review process verified at publons
Indexed In
- CAS Source Index (CASSI)
- Index Copernicus
- Google Scholar
- Sherpa Romeo
- Academic Journals Database
- Open J Gate
- Genamics JournalSeek
- JournalTOCs
- ResearchBible
- China National Knowledge Infrastructure (CNKI)
- Ulrich's Periodicals Directory
- Electronic Journals Library
- RefSeek
- Directory of Research Journal Indexing (DRJI)
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Scholarsteer
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- Euro Pub
- ICMJE
Useful Links
Related Subjects
Share This Page
C18-bound partially sub-1�¼m porous silica monolith particles as low cost HPLC-stationary phase of excellent chromatographic performance and fast HPLC analysis
6th International Conference and Exhibition on Analytical & Bioanalytical Techniques
Faiz Ali and Won Jo Cheong
Inha University, South Korea
ScientificTracks Abstracts-Workshop: J Anal Bioanal Tech
Abstract
Miniaturized partially sub-1�¼m porous silica monolith particles with large pore size, exhibiting excellent chromatographic performance have been synthesized in a relatively large scale by an elaborated sol-gel procedure. The resultant silica monolith particles were chemically modified with chloro-dimethyl-octadecylsilane (C18), and end-capped with a mixture of hexamethyldisilazane and chlorotrimethylsilane. Very good separation efficiency (185,000/m) and resolution (6.05) were achieved when the C18-bound phase was evaluated for a test mixture of five benzene derivatives after packing in a stainless steel column (1.8 mm �� 150 mm). The optimized elution conditions were found to be 70/30 (v/v) acetonitrile/water with 0.1% TFA at a flow rate of 25 �¼L/min. The column was also evaluated for fast HPLC analysis using a flow rate of 100 �¼L/min where all the five analytes were eluted in three minutes with still reasonable efficiency (Ca. 96000/m) and excellent resolution within the pressure limit of conventional HPLC. The strategy of particle size reduction combined with C18 modification along with large pores and monolithic architecture has resulted in a useful stationary phase (C18-bound silica monolith particles) of low production cost showing excellent chromatographic performance capable of fast HPLC analysis.Biography
Email: faizecs@yahoo.com, faizy186@gmail.com
