Journal of Biotechnology & Biomaterials
Open Access

Abstract

In orthopaedic surgery a transition to improve current orthopedic procedures is underway. Surgical techniques, instruments and implants have been greatly refined and improvements in imaging accuracy, namely magnetic resonance (MR) can now clearly identify pathology. The final frontier is to improve biology and hopefully healing. The use of biological materials to foster improved outcomes has been highlighted by major scientific breakthroughs of which have defined the critical pathways of healing and regeneration. The list includes blood-derived preparations, growth factors, bone marrow preparations and expanded stem cells. These biologic adjuncts can provide effective treatments during surgery or during the postoperative period. It is likely that biologic treatments will actively enhance many areas of orthopedic surgery to improve the healing capabilities of currently performed surgical procedures today and in the future. This review will systematically assess the peerreviewed evidence based literature highlighting advances in both pre-clinical studies and clinical trials involving biological substances in the treatment of meniscus, ligament and articular cartilage surgical repair.

Biography

Email: doctormurrell@gmail.com