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The objective of this study was to investigate the role of lumbar paraspinal muscles
(PSMs) in the progression of different types of spondylolisthesis by examining the
correlation between lumbar PSM cross-sectional area (CSA) and slip percentage (SP)
in degenerative spondylolisthesis (DS) and isthmic spondylolisthesis (IS). A multicenter
retrospective analysis was carried out including 219 subjects diagnosed with lumbar
spondylolisthesis. The DS group had 125 subjects and the IS group had 94 subjects.
Using T2-weighted axial MRI images, CSAs of the psoas major (PM), multifidus (MU),
and erector spinae (ES) were measured and divided by L5 vertebral body (VB) CSA to
eliminate biases arising from the physical build of subjects. SP was measured using sagittal
T2 weighted images. Correlations between muscle CSA ratio and SP were calculated in
each group. Regression analysis was performed to predict the influence of each muscle
CSA/VB CSA ratio on SP. No significant correlation was found in the DS group between
any of the muscle CSA ratios and SP. Both PM/VB ratio (r=-0.24, p=0.021) and MU/VB
ratio (r=-0.26, p=0.012) were negatively correlated with SP in the IS group. MU had more
influence on SP than PM in the IS group (regression coefficient MU/VB: -8.08, PM/VB:
-4.34). Both PM and MU muscle CSA ratios were negatively correlated with SP in the
isthmic group. MU had more influence on SP than PM. No muscles had any correlations
with SP in the degenerative group. This discrepancy between the two groups suggests
exercise programs or interventions intended to prevent progression of IS and DS should
be distinguished in clinical practice.
Biography
Ye-Ji Yoon has graduated Kyung Hee University College of Korean Medicine and is in Residency training at Kyung Hee University Hospital at Gangdong, Department of Korean Rehabilitation Medicine.