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Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease in gastrointestinal tract. The clinical signs of IBD
include chronic diarrhea, with or without mucous and/or with or without rectal bleeding. It hasn�t surely been known that
there is a positive correlation between clinical sign and colorectal mucosal lesion severity in the IBD patients. This study
aims to determine the relationship between clinical sign in inflammatory bowel disease patients with the varying colorectal
mucosal lesion. The study was conducted in a retrospective cross section using the medical record data from both inpatient
and outpatient with IBD at the Sardjito General Hospital from January 2012 until July 2014. From 65 data (42 men, 23 women
and age 18 to 97 years old (49.94�±18.25)), there was an insignificant weak positive correlation between clinical signs and lesion
severity in IBD (p=0.0916, r=0.211), also in proctitis (p=0.1543, r=0.2876). Meanwhile, in left-sided colitis, the correlation is
insignificant and has a very weak positive correlation (p=0.9518, r=0.0125). The only significant and stronger correlation is
the correlation between rectal bleeding and lesion severity in the proctitis patients with p=0.0053 and r=0.5310. So, it can be
concluded that there was an insignificant weak positive correlation between clinical signs and lesion severity in IBD, except for
the proctitis, where the correlation between rectal bleeding and lesion severity was rather high. From this conclusion we can
assume that clinical signs only, cannot reflect the disease severity of IBD, with the exception of proctitis where the severity of
rectal bleeding can also depict the severity of the lesion.