ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
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Association between clinical sign and colorectal mucosal lesion severity in patients with inflammatory bowel disease

8th International Conference on Clinical Gastroenterology & Hepatology

Inggar Armytasari

Gadjah Mada University, Indonesia

Posters & Accepted Abstracts: J Gastrointest Dig Syst

DOI: 10.4172/2161-069X.C1.041

Abstract
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease in gastrointestinal tract. The clinical signs of IBD include chronic diarrhea, with or without mucous and/or with or without rectal bleeding. It hasnâ��t surely been known that there is a positive correlation between clinical sign and colorectal mucosal lesion severity in the IBD patients. This study aims to determine the relationship between clinical sign in inflammatory bowel disease patients with the varying colorectal mucosal lesion. The study was conducted in a retrospective cross section using the medical record data from both inpatient and outpatient with IBD at the Sardjito General Hospital from January 2012 until July 2014. From 65 data (42 men, 23 women and age 18 to 97 years old (49.94�±18.25)), there was an insignificant weak positive correlation between clinical signs and lesion severity in IBD (p=0.0916, r=0.211), also in proctitis (p=0.1543, r=0.2876). Meanwhile, in left-sided colitis, the correlation is insignificant and has a very weak positive correlation (p=0.9518, r=0.0125). The only significant and stronger correlation is the correlation between rectal bleeding and lesion severity in the proctitis patients with p=0.0053 and r=0.5310. So, it can be concluded that there was an insignificant weak positive correlation between clinical signs and lesion severity in IBD, except for the proctitis, where the correlation between rectal bleeding and lesion severity was rather high. From this conclusion we can assume that clinical signs only, cannot reflect the disease severity of IBD, with the exception of proctitis where the severity of rectal bleeding can also depict the severity of the lesion.
Biography

Email: i.armyta@gmail.com

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