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The World Health Organization has considered obesity to be the �non-infectious epidemic of the 21st century� and one of the
principal chronic health problems worldwide. Obesity is a chronic multifactorial and complex disease that develops through the
interaction of genotype and environment. The therapeutic approach should take into account cultural alimentary beliefs to improve
a lifestyle intervention. Health-related quality of life scales are being used increasingly to assess the health in population and analyze
the effectiveness of health interventions. The �subjective well-being� has two components: Emotional and cognitive approach. This
research is a cross sectional descriptive study with 276 users of the Primary Health Centre �OfraDelicias-Miramar�, in Santa Cruz de
Tenerife (Spain), in the first quarter of 2016. The sample consists of 52% normal weight (Body Mass Index-BMI <25) and 48% nonnormal
weight: 27% overweight (BMI 25-30) and 21% obese (BMI>30). 60% were female and 40% were male aged between 19 and 75
years old (42.3�±12.73). Instruments used were: Satisfaction with life scale (SWLS) and health-related quality-of-life (EQ-5). EQ-5 is a
simple and widely used multi-attribute utility model that assesses 5 dimensions: Mobility, self-care, usual activities, pain/discomfort
and anxiety/depression. SWLS is a five-item scale designed to measure a person�s global judgment (cognitive) of satisfaction with
their life. Additionally, the satisfaction with life scale has been found to be positively associated at statistically significant levels with
other measures of subjective wellbeing and negatively associated with measures of psychopathology. It is a valid and reliable measure
of satisfaction with life (alphaCronbach=0.97) and test-retest stability (0,82). Results show that there are some relationships between
BMI and health utility scores. As regards EQ-5, obese sample has lower quality of life than both normal and overweight group. There
are significant differences (p<0,05) in 3 items: Mobility, usual activities and discomfort between the 3 groups. In all items, obese
sample score higher than normal and overweight sample. Therefore, obese sample have more problems to walk, more problems to do
ordinary activities and more pain/discomfort than normal weight. In relation to the SWLS, there are significant differences between
normal weight sample and both obese and overweight sample, in first item: �In most ways my life is close to my ideal�. The normal
weight sample scores higher in this item than the other samples. In conclusion, subjective well-being has become a major topic in
studies on chronic diseases, as obesity. In this research, obesity and overweight samples are related to better subjective well-being
than normal weight sample. Longitudinal research that examine the pattern of obesity and the development of well-being is needed,
which would beimportant with regard to future treatment, prevention and not underestimating the cost-utility of interventions for
obesity treatment.