Journal of Analytical & Bioanalytical Techniques
Open Access

Abstract

Headspace (HS) extraction is a 3-phase extraction technique from a sample donor phase to a HS above the donor then from the HS to an acceptor phase. HS extraction is fit for volatile/semi-volatile compounds in a complex matrix. Recently, HS single drop microextraction (SDME) has been demonstrated using a drop of an acceptor phase hanging at the inlet tip of a capillary for the subsequent capillary electrophoresis (CE). However, it is difficult to hang a drop of very small volume in the HS of high temperature stably for a long extraction, and we introduced a novel and simple scheme of HS extraction, HS in-tube microextraction (ITME). Without hanging a drop, the liquid inside a separation capillary for CE is used as an acceptor phase. HS-ITME-CE was first demonstrated in the analysis of chlorophenols in wine. As a second application of HS- ITME, neutral organic pollutant such as BTEX (benzene, toluene, ethyl benzene, and xylene) is extracted from an aqueous sample to a surfactant solution inside a separation capillary. The extracts were then analyzed with a micellar electrokinetic chromatography mode of CE.

Biography

Sung Min Cho is doing undergraduate course in Seoul National University.