Toxicology: Open Access
Open Access

Abstract

Modafinil, a non-amphetamine psycho-stimulant, is indicated for narcolepsy, shift work sleep disorder and severe obstructive sleep apnea syndrome. Modafinil is prescribed at the dose of 100 mg once in a day or as two doses, 12 hours apart in a day. Unlike classical stimulant medications like methylphenidate, Modafinil has been thought to produce its wake-promoting effects independent of dopaminergic actions it has also been found that it reduces cocaine dependence and withdrawal phenomenon. Modafinil is a very beneficial medication and this particular finding in and of itself should not affect the way it is prescribed for the treatment of narcolepsy or even for the treatment in some instances off-label for (attention-deficit/hyperactivity disorder) ADHD or for cognitive impairment in patients with schizophrenia, because under those conditions, the patient is being monitored properly. However, it is directly pertinent to the concept of the misuse of Modafinil, which is increasingly being utilized by healthy individuals with the expectation of improved cognitive performance. Modafinil is claimed to have very low liability for abuse and dependence.

Biography

Soma Sri Harsha is currently pursuing his MBBS from Saveetha Medical College, SIMATS. His area of research is in the field of drug development, under the mentorship of Dr. V Krishnan, Department of Pharmacology, SIMATS in India.
Email:somasriharsha1012@gmail.com